ABSTRACT
Botulinum toxin type A (BTA) has analgesic effect independent of its action in muscle tone, inhibiting the release of neurotransmitters (substance P-glutamate) and neuropeptides of nociceptors. Objective: To characterize infiltration procedures with Botox® in patients with chronic pain refractory to treatment. Method: Observational-cross-retrospective study. Infiltrations with botox procedures performed in Hospital Clínico Mutual de Seguridad, between 01.01.2014 and 30.04.2015 were analyzed. Medical record data were extracted. Information analyzed with Excel2013® using Chi-square test (p <0.05). Results: 31 patients treated, 83.9 percent male. Average age 51 years (SD ± 11.9yo). Diagnostics causes of pain: post-traumatic pain and myofascial syndrome (25.8 percent); complex regional pain syndrome (16.1 percent) and partial hand amputation (12.9 percent). Predominant type of pain: neuropathic pain (64.5 percent). Common procedures: median nerve blockade (21.2 percent) and infiltration of lumbar back trigger points (15.4 percent). 77.4 percent reported good pain control, crisis decreased 74.2 percent and 71 percent decreases opioid use. Return work was effective in 64.5 percent of patients. 93.6 percent satisfactorily tolerated the procedure, 9.7 percent showed fewer adverse effects. The subgroup neuropathic pain had significantly worse results regarding mixed pain subgroup (p <0.05). Discussion: In this study, the use of BTA in chronic pain proved to be a safe and effective procedure for the management of chronic musculoskeletal pain...
Subject(s)
Humans , Male , Adult , Female , Middle Aged , Chronic Pain/drug therapy , Neuromuscular Agents/therapeutic use , Botulinum Toxins, Type A/therapeutic use , Cross-Sectional StudiesABSTRACT
Introducción: La obesidad mórbida es una patología de creciente consulta en nuestro medio a la cual los servicios de salud público no están ajenos. En la actualidad la cirugía ha demostrado ser el tratamiento más eficaz a largo plazo. Objetivos: Informar los resultados obtenidos en el tratamiento de obesos mórbidos sometidos a cirugía abierta en un servicio hospitalario público regional. Material y método: Se analiza en forma prospectiva los primeros 100 pacientes sometidos a cirugía bariátrica en el Hospital de Coquimbo entre Septiembre de 1998 y Diciembre de 2005. Se usaron 3 técnicas en forma consecutiva. En todas ellas se efectuó el bypass gástrico empleando anastomosis en Y de Roux con asa larga de 160 cm. Para los análisis estadísticos se emplearon los test de ANOVA y Student. Resultados: El 83 por ciento de los operados fueron mujeres. El IMC preoperatorio promedio fue de 46 kg/m², siendo un 29 por ciento superobesos (IMC>50). La estadía postoperatoria promedio fue de 7,6 días. Complicaciones postoperatorias precoces hubo en el 5 por ciento. No se registró mortalidad operatoria en esta serie. El promedio de reducción de exceso de peso fue de 60 por ciento a los 6 meses, 72 por ciento al año y 66 por ciento a los 3 años. Conclusiones: Los resultados obtenidos en un hospital público regional en relación a la cirugía bariátrica son absolutamente comparables a estudios nacionales e internacionales, tanto en la reducción de peso como en la morbimortalidad.
Background: Surgery is the most effective treatment in the long run, for morbid obesity. Aim: To report the results of open bariatric surgery for morbid obesity in a regional public hospital. Material and methods: Prospective study of the first 100 patients aged 14 to 62 years (84 percent women) undergoing bariatric surgery in Coquimbo hospital between September 1998 and December 2005. A Horizontal Gastroplasty without gastric resection was done in 13 patients, a 6/7 Gastrectomy in 58 and a 9/10 Gastrectomy in 29. A gastric bypass with Roux-en-Y anastomosis with a 160 cm long loop, was always performed. Results: Preoperative body mass index (BMI) was 46 kg/m². Twenty nine percent had a BMI over 50 kg/m². The average postoperative hospital stay was 7.6 days. Five percent had early complications. No patients died. The average excess weight loss at 6 months, one and three years after surgery was 60, 72 and 66 percent respectively. Patients subjected to a gastric resection had a higher percentage of excess weight loss than gastroplasty after 1 year (p <0.01). After 3 years, the greatest excess weight loss was seen in patients with a BMI below 50 kg/m² subjected to Gastrectomy. The smaller excess weight loss was observed in patients with a BMI over 50 kg/m² subjected to Gastroplasty. After 6 months and 1 year, patients undergoing larger Gastrectomies (9/10) had a significantly greater percentage weight loss than those subjected to smaller resections (6/7). Conclusions: These results obtained in a public hospital surgery service with bariatric procedures are comparable with those of national and international studies, both in terms of weight loss and complications.